Just make sure you have fresh fluids (oil, brake, clutch), top off your power steering, maybe bleed and top your coolant if it's been a while. Check the car over for any possible mechanical issues.
I've driven WNY to Southern RI a couple times, which is almost 8 hours, and I had a boosted Civic at the time. No issues as long as you maintain it well
EDIT: Totally forgot to mention... check the air pressure in your tires and make sure they're to spec!