A complete phase cancellation is when two sound waves meet at a point and they are 180 degrees out of phase. If they are in-phase they will add and cause a 6dB increase in amplitude. This interaction could be from two drivers reproducing the same frequencies interacting or from a reflection off a surface interacting with the driver that produced it.
It all depends becuase of the placement and environment. Some materials absorb sound, some reflect, and some are of no consequence because of their size in relationship to the frequency that it is interacting with.
Say a sub is placed in the trunk aimed at the rear of the trunk. If it is 1/4 wavelength from the surface and it reflects back to the sub it will have traveled 1/2 wavelength, which means the sound wave will be 180 degrees out of phase and will cause complete cancellation. Now, if by the time the reflected wave reaches the driver and it is no longer producing that frequency, it won't cancel.
Phase cancellation between two subs is harder to aviod than with other drivers because low frequencies are omni-directional.
This is topic can get much more in-depth, this is just a quick overview.